Whether cancer patients survive chemotherapy is down to your genes, scientists have claimed.
Researchers have identified an eight gene 'signature' which can predict the length of relapse-free survival after the treatment.
They found patients whose gene signature put them in the low-risk group had a longer relapse free survival than the high-risk group.
Researchers have identified an eight gene 'signature' which can predict the length of relapse-free survival after the treatment
They first identified genes that were involved in cellular invasion, a property of many cancer cells, using the National Cancer Institute's 60 human cancer cell line panel (NCI-60).
Comparing the pattern of activation of each of these genes in different cell lines with how these cell lines responded to 99 different anti-cancer drugs, helped narrow down the list of genes to just those which could potentially influence the outcome of chemotherapy.
Testing this link, Prof Ker-Chau Li, from Academia Sinica and UCLA, said: 'Our study found eight genes which were involved in invasion, and the relative activation of these genes correlated to chemotherapy outcome, including the receptor for growth factor EGF.
Researchers studied the gene reaction to 99 anti-cancer drugs
Read more: http://www.dailymail.co.uk/sciencetech/article-2309515/Chemotherapy-survival-genes-claim-scientists.html#ixzz2QaUI4NxF
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