- Family history of cancer: Women who have a mother, daughter, or sister with ovarian cancer have an increased risk of the disease. Also, women with a family history of cancer of the breast, uterus, colon, or rectum may also have an increased risk of ovarian cancer.
- Personal history of cancer: Women who have had cancer of the breast, uterus, colon, or rectum have a higher risk of developing ovarian cancer.
- Age over 55: Ovarian cancer rates increase with age. Most women are over age 55 when diagnosed with ovarian cancer.
- Never pregnant: Older women who have never been pregnant have an increased risk of ovarian cancer.
- Menopausal Hormonal Therapy: Some studies have suggested that women who take estrogen by itself (estrogen without progesterone) for 10 or more years may have an increased risk of ovarian cancer.
Scientists have also studied whether taking certain fertility drugs, using talcum powder, or being obese are risk factors. It is not clear whether these are risk factors, but if they are, they are not strong risk factors.
Having a risk factor does not mean that a woman will get ovarian cancer. In fact, most women who have risk factors from the list above do not develop ovarian cancer. In addition, women who do develop ovarian cancer often have no known risk factors, except that they are older than 55. Women who think they may be at risk of ovarian cancer should talk with their doctor.